Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647200 | 0.86 | MAPT (0.46) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL1787107 | 0.84 | GAA (0.46) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL9247954 | 0.83 | HPGD (0.56) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL8930238 | 0.81 | LMNA (0.44) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL6740081 | 0.81 | LMNA (0.45) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL4681898 | 0.80 | MAPT (0.51) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL3657255 | 0.80 | GAA (0.43) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL13479860 | 0.79 | MAPT (0.46) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL4684781 | 0.79 | MAPT (0.50) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL9248009 | 0.79 | LMNA (0.48) | LMNAMAPTHPGDSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138527-A2 | Herbicidal pyrazole derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-04-24 | — | — | EP | disclosed |