Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.55 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020321 | 1.00 | TBXAS1 (0.55) | TBXAS1SLC13A5AKR1C3L3MBTL1HPGD | |
| SCHEMBL11022887 | 0.88 | TBXAS1 (0.58) | TBXAS1SLC13A5L3MBTL1HPGDMAPK1 | |
| SCHEMBL11022833 | 0.88 | MAPK1 (0.43) | TBXAS1SLC13A5L3MBTL1HPGDMAPK1 | |
| SCHEMBL11022889 | 0.88 | TBXAS1 (0.58) | TBXAS1SLC13A5L3MBTL1HPGDMAPK1 | |
| SCHEMBL11022827 | 0.88 | MAPK1 (0.43) | TBXAS1SLC13A5L3MBTL1HPGDMAPK1 | |
| SCHEMBL11022788 | 0.83 | TBXAS1 (0.60) | TBXAS1AKR1C3 | |
| SCHEMBL11022800 | 0.83 | TBXAS1 (0.60) | TBXAS1AKR1C3 | |
| Hydrochloric Acid SCHEMBL11023847 | 0.81 | TBXAS1 (0.62) | TBXAS1AKR1C3 | |
| Hydrochloric Acid SCHEMBL11023874 | 0.81 | TBXAS1 (0.62) | TBXAS1AKR1C3 | |
| SCHEMBL11039471 | 0.81 | MAPT (0.41) | TBXAS1L3MBTL1HPGDMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153678-A1 | Cinnamic acid derivatives, processes for the preparation thereof and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1985-09-04 | — | — | EP | disclosed |