Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | PGR | P06401 | 3/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MLNR | O43193 | 1/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021243 | 0.92 | CYP3A4 (0.73) | ARLMNACYP3A4PGRNR3C1 | |
| SCHEMBL11020551 | 0.89 | AR (0.63) | ARLMNACYP3A4PGRNR3C1 | |
| SCHEMBL11022317 | 0.87 | CYP19A1 (0.56) | ARLMNACYP3A4PGRNR3C1 | |
| SCHEMBL6801424 | 0.85 | AR (0.82) | ARLMNACYP3A4PGRNR3C1 | |
| SCHEMBL11020597 | 0.82 | AR (0.54) | ARLMNACYP3A4PGRNR3C1 | |
| SCHEMBL11023303 | 0.82 | NR3C2 (0.49) | ARLMNACYP3A4PGRNR3C1 | |
| SCHEMBL10703308 | 0.81 | AR (0.54) | ARLMNACYP3A4PGRNR3C1 | |
| SCHEMBL2823016 | 0.81 | LMNA (0.56) | ARLMNACYP3A4PGRNR3C1 | |
| SCHEMBL6447130 | 0.81 | CYP19A1 (0.61) | ARLMNACYP3A4PGRNR3C1 | |
| SCHEMBL11020426 | 0.79 | AR (0.59) | ARLMNACYP3A4PGRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054786-B1 | 6-ALPHA-METHYL HYDROCORTISONE DERIVATIVES, THEIR PREPARATION AND THEIR UTILIZATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | disclosed |