Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 7/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021896 | 0.98 | ADORA3 (0.48) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11139615 | 0.95 | ADORA3 (0.47) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11018894 | 0.94 | ADORA3 (0.49) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11020606 | 0.93 | CA12 (0.51) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11145027 | 0.92 | ADORA3 (0.47) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11154728 | 0.91 | CNR2 (0.54) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11152270 | 0.89 | CNR2 (0.53) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11157233 | 0.89 | CNR2 (0.53) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11155367 | 0.89 | CNR2 (0.53) | ADORA3ADORA2AADORA1CA12CA1 | |
| SCHEMBL11157229 | 0.89 | CNR2 (0.53) | ADORA3ADORA2AADORA1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039913-B1 | TETRAZOLYLCOUMARIN DERIVATIVES, PROCESS FOR PREPARING THE SAME AND COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1985-01-23 | — | — | EP | disclosed |
| US-4406908-A | Tetrazolylcoumarin derivatives and antiallergic compositions containing the same | KAKENYAKU KAKO CO., LTD. (JP) | 1983-09-27 | — | — | US | disclosed |
| EP-0039913-A1 | Tetrazolylcoumarin derivatives, process for preparing the same and composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1981-11-18 | — | — | EP | disclosed |