Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TTR | P02766 | 1/20 | 0.69 |
| ▸ | PPOX | P50336 | 1/20 | 0.69 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452357 | 0.91 | TDP1 (0.67) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11023773 | 0.88 | MEN1 (0.70) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen-Methyl SCHEMBL30749491 | 0.87 | MEN1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen-Methyl SCHEMBL31614705 | 0.87 | MEN1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen-Methyl SCHEMBL39092 | 0.87 | MEN1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL39607 | 0.87 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL29366195 | 0.87 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL16881788 | 0.87 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL30120750 | 0.87 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11020865 | 0.87 | MEN1 (0.71) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066989-B1 | NOVEL SUBSTITUTED NITRODIPHENYL ETHERS, HERBICIDAL COMPOSITIONS CONTAINING THEM, A PROCESS FOR THE PREPARATION OF THE NITRODIPHENYL ETHERS AND THE USE THEREOF FOR COMBATING WEEDS | ROHM AND HAAS COMPANY (US) | 1985-03-20 | — | — | EP | disclosed |
| EP-0066989-A2 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, a process for the preparation of the nitrodiphenyl ethers and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1982-12-15 | — | — | EP | disclosed |