Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | TTR | P02766 | 1/20 | 0.71 |
| ▸ | PPOX | P50336 | 1/20 | 0.71 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023773 | 0.91 | MEN1 (0.70) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10451961 | 0.91 | MEN1 (0.69) | MEN1KMT2ATDP1TTRPPOX | |
| Acifluorfen-Methyl SCHEMBL31614705 | 0.89 | MEN1 (0.78) | MEN1KMT2ATDP1TTRPPOX | |
| Acifluorfen-Methyl SCHEMBL39092 | 0.89 | MEN1 (0.78) | MEN1KMT2ATDP1TTRPPOX | |
| Acifluorfen-Methyl SCHEMBL30749491 | 0.89 | MEN1 (0.78) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11024062 | 0.88 | MEN1 (0.66) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11441530 | 0.87 | TDP1 (0.82) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL6752643 | 0.87 | MEN1 (0.82) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11020633 | 0.87 | TDP1 (0.69) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11361666 | 0.86 | TDP1 (0.68) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066989-B1 | NOVEL SUBSTITUTED NITRODIPHENYL ETHERS, HERBICIDAL COMPOSITIONS CONTAINING THEM, A PROCESS FOR THE PREPARATION OF THE NITRODIPHENYL ETHERS AND THE USE THEREOF FOR COMBATING WEEDS | ROHM AND HAAS COMPANY (US) | 1985-03-20 | — | — | EP | disclosed |
| EP-0066989-A2 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, a process for the preparation of the nitrodiphenyl ethers and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1982-12-15 | — | — | EP | disclosed |