Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477749 | 0.76 | ADRB2 (0.46) | ADRB3ADRB2ADRB1KDM4ECYP2D6 | |
| SCHEMBL14030635 | 0.76 | ADRB2 (0.50) | ADRB3ADRB2ADRB1KDM4ECYP2D6 | |
| SCHEMBL19422886 | 0.74 | ADRB2 (0.48) | ADRB3ADRB2ADRB1KDM4ECYP2D6 | |
| SCHEMBL4452011 | 0.73 | ADRB2 (0.65) | ADRB3ADRB2ADRB1KDM4ECYP2D6 | |
| SCHEMBL10477764 | 0.72 | ADRB2 (0.55) | ADRB3ADRB2ADRB1KDM4ECYP2D6 | |
| SCHEMBL4455098 | 0.72 | ADRB2 (0.68) | ADRB3ADRB2ADRB1KDM4ECYP2D6 | |
| SCHEMBL10477708 | 0.71 | ADRB2 (0.80) | ADRB3ADRB2ADRB1KDM4ECYP2D6 | |
| SCHEMBL10477723 | 0.71 | ADRB2 (0.80) | ADRB3ADRB2ADRB1KDM4ECYP2D6 | |
| SCHEMBL4451888 | 0.71 | ADRB2 (0.72) | ADRB3ADRB2ADRB1KDM4ECYP2D6 | |
| SCHEMBL4637738 | 0.71 | ADRB2 (0.41) | ADRB3ADRB2ADRB1KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162576-A1 | Ethanolamine compounds | GLAXO GROUP LIMITED (GB) | 1985-11-27 | — | — | EP | disclosed |