Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.50 |
| ▸ | SQLE | Q14534 | 5/20 | 0.48 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | FNTB | P49356 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018787 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL5373410 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL3087751 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11023522 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23925025 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL5373407 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23924906 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL25220642 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23925202 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL28971392 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050853-B1 | POLYPRENYL KETONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, A PHARMACEUTICAL PREPARATION CONTAINING SAID DERIVATIVE AND THE USE OF THE SAME | Eisai Co., Ltd. (JP) | 1985-01-02 | — | — | EP | claimed |
| US-4456558-A | ANTITUMOR, HYPOTENSIVE | EISAI CO., LTD. (JP) | 1984-06-26 | — | — | US | claimed |
| EP-0050853-A1 | Polyprenyl ketone derivatives, a process for their preparation, a pharmaceutical preparation containing said derivative and the use of the same | Eisai Co., Ltd. (JP) | 1982-05-05 | — | — | EP | claimed |
| EP-0050853-B1 | POLYPRENYL KETONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, A PHARMACEUTICAL PREPARATION CONTAINING SAID DERIVATIVE AND THE USE OF THE SAME | Eisai Co., Ltd. (JP) | 1985-01-02 | — | — | EP | disclosed |
| US-4468459-A | Process for the preparation of polyprenyl ketone derivatives | EISAI CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4456558-A | ANTITUMOR, HYPOTENSIVE | EISAI CO., LTD. (JP) | 1984-06-26 | — | — | US | disclosed |
| EP-0050853-A1 | Polyprenyl ketone derivatives, a process for their preparation, a pharmaceutical preparation containing said derivative and the use of the same | Eisai Co., Ltd. (JP) | 1982-05-05 | — | — | EP | disclosed |