Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.50 |
| ▸ | SQLE | Q14534 | 5/20 | 0.48 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | FNTB | P49356 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018787 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL3087751 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11023522 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23925025 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL5373407 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23924906 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL25220642 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23925202 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11021028 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL28971392 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456558-A | ANTITUMOR, HYPOTENSIVE | EISAI CO., LTD. (JP) | 1984-06-26 | — | — | US | claimed |
| EP-0050853-A1 | Polyprenyl ketone derivatives, a process for their preparation, a pharmaceutical preparation containing said derivative and the use of the same | Eisai Co., Ltd. (JP) | 1982-05-05 | — | — | EP | claimed |
| US-7276622-B2 | Method for producing oxygen-containing compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-02 | — | — | US | disclosed |
| US-20060173221-A1 | Method for producing oxygen-containing compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-08-03 | — | — | US | disclosed |
| EP-1609777-A1 | METHOD FOR PRODUCING OXYGEN-CONTAINING COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-5354874-A | Intermediates for Sarcophytol A; antitumor, anticarcinogenic agent | MITSUBISHI KASEI CORPORATION (JP) | 1994-10-11 | — | — | US | disclosed |
| US-5324869-A | Chemical intermediates for sarcophytol a | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-28 | — | — | US | disclosed |
| US-5304661-A | Chemical intermediate for sarcophytol a | MITSUBISHI KASEI CORPORATION (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5245085-A | Chemical intermediates for sarcophytol A, an anticancer and antitumor agent | MITSUBISHI KASEI CORPORATION (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0050853-B1 | POLYPRENYL KETONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, A PHARMACEUTICAL PREPARATION CONTAINING SAID DERIVATIVE AND THE USE OF THE SAME | Eisai Co., Ltd. (JP) | 1985-01-02 | — | — | EP | disclosed |
| US-4468459-A | Process for the preparation of polyprenyl ketone derivatives | EISAI CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4456558-A | ANTITUMOR, HYPOTENSIVE | EISAI CO., LTD. (JP) | 1984-06-26 | — | — | US | disclosed |
| EP-0050853-A1 | Polyprenyl ketone derivatives, a process for their preparation, a pharmaceutical preparation containing said derivative and the use of the same | Eisai Co., Ltd. (JP) | 1982-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173221-A1 | Method for producing oxygen-containing compound | GPX4, DUOX2, SCO2 | KMT2A 2326/4885MAPT 3720/4885MEN1 2707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.