Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 15/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 15/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018220 | 1.00 | PPARG (0.49) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL11019932 | 1.00 | PPARG (0.49) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL10953472 | 0.85 | GRM2 (0.65) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL6242750 | 0.81 | GRM2 (0.69) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL9176150 | 0.80 | CYSLTR2 (0.46) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL9176148 | 0.80 | CYSLTR2 (0.46) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL11019704 | 0.80 | PPARG (0.60) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL6244992 | 0.80 | GRM2 (0.72) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL9821841 | 0.79 | PPARG (0.55) | PPARGPPARDPPARAGRM2LMNA | |
| SCHEMBL9191892 | 0.78 | PPARG (0.57) | PPARGPPARDPPARAGRM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146333-A1 | Organic compounds and their pharmaceutical use | Lilly Industries Limited (GB) | 1985-06-26 | — | — | EP | disclosed |