Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176150 | 1.00 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1PPARGPPARAPPARD | |
| SCHEMBL11018220 | 0.80 | PPARG (0.49) | CYSLTR2CYSLTR1PPARGPPARAPPARD | |
| SCHEMBL11021045 | 0.80 | PPARG (0.49) | CYSLTR2CYSLTR1PPARGPPARAPPARD | |
| SCHEMBL11019932 | 0.80 | PPARG (0.49) | CYSLTR2CYSLTR1PPARGPPARAPPARD | |
| SCHEMBL9174150 | 0.75 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1GRM2LMNA | |
| SCHEMBL9174143 | 0.75 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1GRM2LMNA | |
| SCHEMBL29030433 | 0.75 | PIM1 (0.46) | — | |
| SCHEMBL9175712 | 0.74 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1PPARGPPARAPPARD | |
| SCHEMBL6242750 | 0.73 | GRM2 (0.69) | CYSLTR2CYSLTR1PPARGPPARAPPARD | |
| SCHEMBL9173414 | 0.73 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393768-A | Treating hypersensitivity reactions such as asthma | ELI LILLY AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5105017-A | Antiallergens | ELI LILLY AND COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0132366-A2 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |