Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Methoxyethanol SCHEMBL11144253 | 0.94 | CNR2 (0.45) | CNR2GPR35ADORA3CA12CA1 | |
| SCHEMBL11153000 | 0.89 | CNR2 (0.50) | CNR2GPR35ADORA3CA12CA1 | |
| SCHEMBL11018894 | 0.88 | ADORA3 (0.49) | CNR2GPR35ADORA3CA12CA1 | |
| SCHEMBL11150783 | 0.88 | CNR2 (0.57) | CNR2GPR35ADORA3CA12CA1 | |
| SCHEMBL11020844 | 0.87 | CNR2 (0.47) | CNR2GPR35ADORA3CA12CA1 | |
| SCHEMBL11020606 | 0.87 | CA12 (0.51) | CNR2GPR35ADORA3CA12CA1 | |
| SCHEMBL11023658 | 0.87 | CA12 (0.48) | CNR2GPR35ADORA3CA12CA1 | |
| SCHEMBL11020681 | 0.86 | ADORA3 (0.47) | CNR2GPR35ADORA3CA12CA1 | |
| SCHEMBL11154728 | 0.86 | CNR2 (0.54) | CNR2GPR35ADORA3CA12CA1 | |
| SCHEMBL11152052 | 0.86 | ADORA3 (0.61) | ADORA3CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039913-B1 | TETRAZOLYLCOUMARIN DERIVATIVES, PROCESS FOR PREPARING THE SAME AND COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1985-01-23 | — | — | EP | disclosed |
| US-4406908-A | Tetrazolylcoumarin derivatives and antiallergic compositions containing the same | KAKENYAKU KAKO CO., LTD. (JP) | 1983-09-27 | — | — | US | disclosed |
| EP-0039913-A1 | Tetrazolylcoumarin derivatives, process for preparing the same and composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1981-11-18 | — | — | EP | disclosed |