Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019146 | 0.89 | CYP3A4 (0.54) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL13823084 | 0.82 | CTSK (0.57) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL10618853 | 0.81 | CTSK (0.44) | MEN1KMT2ACTSKCTSSATM | |
| SCHEMBL15080869 | 0.80 | CTSK (0.61) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL30946598 | 0.80 | CTSK (0.61) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL16050481 | 0.79 | CTSK (0.55) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL5075275 | 0.79 | CTSK (0.60) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL7674223 | 0.79 | MAPT (0.61) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL5412160 | 0.79 | MAPT (0.61) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL939737 | 0.79 | MAPT (0.61) | MEN1LMNAKMT2ACTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153418-A1 | MANDELIC ACID DERIVATIVES | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1985-09-04 | — | — | EP | disclosed |