Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.54 |
| ▸ | ANPEP | P15144 | 5/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019928 | 0.90 | DPP4 (0.67) | DPP4ANPEPKEAP1NFE2L2NR1H2 | |
| SCHEMBL11018124 | 0.89 | DPP4 (0.55) | DPP4ANPEPNR1H2NR1H3TYMS | |
| SCHEMBL11018319 | 0.88 | DPP4 (0.54) | DPP4ANPEPNR1H2NR1H3TYMS | |
| SCHEMBL11016971 | 0.86 | DPP4 (0.52) | DPP4ANPEPNR1H2NR1H3TYMS | |
| SCHEMBL11017664 | 0.86 | ANPEP (0.52) | DPP4ANPEPNR1H2NR1H3 | |
| SCHEMBL11018644 | 0.83 | DPP4 (0.57) | DPP4ANPEPKEAP1NFE2L2NR1H2 | |
| SCHEMBL11016509 | 0.81 | DPP4 (0.55) | DPP4ANPEPKEAP1NFE2L2NR1H2 | |
| SCHEMBL11018380 | 0.79 | DPP4 (0.55) | DPP4ANPEPNR1H2NR1H3TYMS | |
| SCHEMBL11019613 | 0.79 | DPP4 (0.55) | DPP4ANPEPNR1H2NR1H3TYMS | |
| SCHEMBL11018036 | 0.78 | DPP4 (0.49) | DPP4ANPEPKEAP1NFE2L2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |