⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665636 | 1.00 | — | — | |
| SCHEMBL8806239 | 0.81 | — | — | |
| SCHEMBL3549920 | 0.81 | — | — | |
| Water SCHEMBL10643662 | 0.80 | — | — | |
| Water SCHEMBL10644392 | 0.80 | — | — | |
| Water SCHEMBL10644904 | 0.80 | — | — | |
| SCHEMBL9664052 | 0.79 | — | — | |
| SCHEMBL9537881 | 0.72 | — | — | |
| SCHEMBL9537931 | 0.71 | — | — | |
| SCHEMBL8807406 | 0.70 | HSP90AA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154132-A1 | 6-Alkylidene penems, their preparation and use, and intermediates | BEECHAM GROUP PLC (GB) | 1985-09-11 | — | — | EP | disclosed |