⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3549920 | 1.00 | — | — | |
| Water SCHEMBL10644392 | 0.99 | — | — | |
| Water SCHEMBL10643662 | 0.99 | — | — | |
| Water SCHEMBL10644904 | 0.99 | — | — | |
| SCHEMBL9324400 | 0.82 | — | — | |
| SCHEMBL9324438 | 0.82 | — | — | |
| Water SCHEMBL9326433 | 0.81 | — | — | |
| SCHEMBL11021669 | 0.81 | — | — | |
| SCHEMBL9664052 | 0.81 | — | — | |
| SCHEMBL9325751 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210814-A1 | 6-(Substituted methylene) penems | BEECHAM GROUP PLC (GB) | 1987-02-04 | — | — | EP | claimed |
| EP-0232966-B1 | Process for the preparation of penem compounds and intermediates for this preparation | BEECHAM GROUP PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| US-5114929-A | Oral administration of antibiotics from an unpressurized container | BEECHAM GROUP P.L.C. (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0291304-B1 | PROCESS FOR THE CONVERSION OF THE E-ISOMER OF 6-(SUBSTITUTED METHYLENE)-2-PENEMS INTO THE Z-ISOMER | BEECHAM GROUP PLC (GB) | 1992-02-26 | — | — | EP | disclosed |
| EP-0291304-A1 | Process for the conversion of the E-isomer of 6-(substituted methylene)-2-penems into the Z-isomer | BEECHAM GROUP PLC (GB) | 1988-11-17 | — | — | EP | disclosed |
| US-4774238-A | BACTERICIDES, BETA-LACTAMASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1988-09-27 | — | — | US | disclosed |
| EP-0232966-A1 | Process for the preparation of penem compounds and intermediates for this preparation | BEECHAM GROUP PLC (GB) | 1987-08-19 | — | — | EP | disclosed |
| EP-0210814-A1 | 6-(Substituted methylene) penems | BEECHAM GROUP PLC (GB) | 1987-02-04 | — | — | EP | disclosed |