Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.52 |
| ▸ | ANPEP | P15144 | 5/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023192 | 0.88 | DPP4 (0.51) | DPP4ANPEPNR1H2NR1H3ALDH1A1 | |
| SCHEMBL11022221 | 0.86 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3MAPT | |
| SCHEMBL11020920 | 0.85 | ANPEP (0.47) | DPP4ANPEPALDH1A1TSHR | |
| SCHEMBL11019207 | 0.83 | DPP4 (0.58) | DPP4ANPEPPLA2G1BATG4BNR1H2 | |
| SCHEMBL11018924 | 0.82 | DPP4 (0.59) | DPP4ANPEPNR1H2NR1H3 | |
| SCHEMBL11019578 | 0.79 | DPP4 (0.53) | DPP4ANPEPNR1H2NR1H3 | |
| SCHEMBL11018345 | 0.78 | DPP4 (0.49) | DPP4ANPEPNR1H2NR1H3ALDH1A1 | |
| SCHEMBL11021713 | 0.77 | DPP4 (0.56) | DPP4ANPEPPLA2G1BATG4BNR1H2 | |
| SCHEMBL11019005 | 0.76 | DPP4 (0.68) | DPP4ANPEPNR1H2NR1H3ELANE | |
| SCHEMBL11018141 | 0.75 | NLRP3 (0.52) | DPP4ANPEPNR1H2NR1H3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |