Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814027 | 0.87 | AOC3 (0.47) | AOC3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9814024 | 0.87 | AOC3 (0.47) | AOC3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9813943 | 0.87 | AOC3 (0.47) | AOC3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9813936 | 0.87 | AOC3 (0.47) | AOC3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9813928 | 0.87 | AOC3 (0.47) | AOC3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10822515 | 0.83 | ADRB3 (0.46) | AOC3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10822511 | 0.83 | ADRB3 (0.46) | AOC3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10822520 | 0.83 | ADRB3 (0.46) | AOC3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10526919 | 0.82 | FFAR1 (0.46) | AOC3KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10526937 | 0.82 | FFAR1 (0.46) | AOC3KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164700-A2 | Bis(beta-hydroxy phenethyl)amines | BEECHAM GROUP PLC (GB) | 1985-12-18 | — | — | EP | disclosed |