Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813936 | 1.00 | AOC3 (0.47) | AOC3ESR1ESR2OPRK1OPRM1 | |
| SCHEMBL9814024 | 1.00 | AOC3 (0.47) | AOC3ESR1ESR2OPRK1OPRM1 | |
| SCHEMBL9813943 | 1.00 | AOC3 (0.47) | AOC3ESR1ESR2OPRK1OPRM1 | |
| SCHEMBL9813928 | 1.00 | AOC3 (0.47) | AOC3ESR1ESR2OPRK1OPRM1 | |
| SCHEMBL9813937 | 0.89 | SLC2A1 (0.47) | — | |
| SCHEMBL9813948 | 0.89 | SLC2A1 (0.47) | — | |
| SCHEMBL11021733 | 0.87 | AOC3 (0.46) | AOC3OPRK1KDM4EMEN1KMT2A | |
| SCHEMBL9813944 | 0.84 | SLC2A1 (0.50) | — | |
| SCHEMBL9813900 | 0.84 | SLC2A1 (0.50) | — | |
| SCHEMBL9813952 | 0.84 | SLC2A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017619-A | Anitdiabetic | HOFFMANN-LA ROCHE INC. (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0198412-B1 | PHENETHANOL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1989-03-22 | — | — | EP | disclosed |
| EP-0198412-A1 | Phenethanol amine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-10-22 | — | — | EP | disclosed |