Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452422 | 0.80 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC18A2CYP2D6MEN1 | |
| SCHEMBL22957765 | 0.75 | SIGMAR1 (0.52) | SIGMAR1TAAR1SLC18A2CYP1A2CYP3A4 | |
| SCHEMBL7956903 | 0.69 | TAAR1 (0.57) | SIGMAR1TAAR1SLC18A2CYP3A4CYP2D6 | |
| SCHEMBL17992755 | 0.69 | TAAR1 (0.57) | SIGMAR1TAAR1SLC18A2CYP3A4CYP2D6 | |
| SCHEMBL8072287 | 0.68 | SIGMAR1 (0.58) | SIGMAR1TAAR1SLC18A2CYP2D6MEN1 | |
| SCHEMBL4785594 | 0.68 | SIGMAR1 (0.64) | SIGMAR1TAAR1SLC18A2CYP2D6MEN1 | |
| SCHEMBL902381 | 0.68 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC18A2CYP2D6MEN1 | |
| SCHEMBL11021208 | 0.68 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC18A2CYP3A4CYP2D6 | |
| SCHEMBL13995832 | 0.67 | ACACB (0.42) | CYP3A4CYP2D6TSHRADRB2 | |
| SCHEMBL21568873 | 0.66 | SIGMAR1 (0.48) | SIGMAR1TAAR1SLC18A2CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158918-A1 | Process for preparing polyphenylene ethers | BASF Aktiengesellschaft (DE) | 1985-10-23 | — | — | EP | disclosed |