Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049838 | 0.91 | SLC29A1 (0.34) | SLC29A1 | |
| SCHEMBL11030154 | 0.89 | SLC29A1 (0.32) | SLC29A1 | |
| SCHEMBL11025913 | 0.88 | SLC29A1 (0.33) | SLC29A1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11031606 | 0.88 | SLC29A1 (0.32) | SLC29A1 | |
| SCHEMBL11315564 | 0.86 | SLC29A1 (0.31) | SLC29A1 | |
| SCHEMBL11047615 | 0.86 | HRH4 (0.40) | SLC29A1ALDH1A1HPGD | |
| SCHEMBL11046910 | 0.85 | HRH4 (0.38) | SLC29A1ALDH1A1HPGD | |
| SCHEMBL11026793 | 0.85 | ALDH1A1 (0.43) | SLC29A1ALDH1A1HPGD | |
| SCHEMBL11052623 | 0.85 | HRH4 (0.41) | SLC29A1ALDH1A1HPGD | |
| SCHEMBL11026806 | 0.84 | HRH4 (0.38) | SLC29A1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055444-B1 | TRISUBSTITUTED PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |
| US-4478833-A | ANTICOAGULANTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0055444-A2 | Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-07-07 | — | — | EP | disclosed |