Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019727 | 0.93 | PDE3B (0.48) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL11020962 | 0.89 | KDM4E (0.42) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL11019774 | 0.87 | PDE3B (0.46) | KDM4EALDH1A1HPGDPDE3BPDE3A | |
| SCHEMBL11018903 | 0.87 | KDM4E (0.41) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL11018107 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL11023149 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL11025640 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL9475077 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL11022787 | 0.81 | PDE3B (0.46) | KDM4EALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL11021105 | 0.81 | PDE3B (0.49) | KDM4EALDH1A1HPGDPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |