Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018477 | 0.92 | L3MBTL1 (0.47) | L3MBTL1MAPTNPSR1KCNA3TDP1 | |
| SCHEMBL11020806 | 0.90 | KCNA3 (0.39) | L3MBTL1MAPTNPSR1KCNA3TDP1 | |
| SCHEMBL11022872 | 0.87 | KDM4E (0.52) | TDP1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL11024159 | 0.85 | MAOB (0.48) | L3MBTL1MAPTHPGDNPC1RAB9A | |
| SCHEMBL11022638 | 0.85 | L3MBTL1 (0.44) | L3MBTL1MAPTNPSR1KCNA3HPGD | |
| SCHEMBL11023064 | 0.81 | L3MBTL1 (0.45) | L3MBTL1MAPTNPSR1KCNA3HPGD | |
| SCHEMBL11020827 | 0.79 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1KCNA3HPGD | |
| SCHEMBL10678890 | 0.78 | L3MBTL1 (0.43) | L3MBTL1MAPTNPSR1KCNA3HPGD | |
| SCHEMBL11021329 | 0.78 | L3MBTL1 (0.43) | L3MBTL1MAPTNPSR1KCNA3TDP1 | |
| SCHEMBL10683857 | 0.77 | L3MBTL1 (0.41) | L3MBTL1MAPTTDP1HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |