Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1091965 | 0.88 | MPL (0.59) | MPLNR4A2 | |
| SCHEMBL1102200 | 0.88 | MPL (0.84) | MPL | |
| SCHEMBL1102144 | 0.86 | MPL (0.77) | MPL | |
| SCHEMBL1091560 | 0.82 | MPL (0.56) | MPLNR4A2 | |
| SCHEMBL1102226 | 0.79 | MPL (0.73) | MPL | |
| SCHEMBL1102179 | 0.77 | MPL (1.00) | MPL | |
| SCHEMBL1102234 | 0.76 | MPL (0.84) | MPL | |
| SCHEMBL1102273 | 0.74 | MPL (0.77) | MPL | |
| SCHEMBL1102097 | 0.74 | MPL (0.44) | MPL | |
| SCHEMBL1105578 | 0.74 | MPL (0.72) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153671-B2 | Heterotetracyclic compounds as TPO mimetics | IRM LLC (BM) | 2012-04-10 | — | — | US | disclosed |