Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.83 |
| ▸ | HTR7 | P34969 | 2/20 | 0.79 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017224 | 1.00 | KDM4E (0.83) | KDM4EHTR7ADRB2ADRB1ALDH1A1 | |
| SCHEMBL11020807 | 1.00 | KDM4E (0.83) | KDM4EHTR7ADRB2ADRB1ALDH1A1 | |
| SCHEMBL11019625 | 1.00 | KDM4E (0.83) | KDM4EHTR7ADRB2ADRB1ALDH1A1 | |
| SCHEMBL11022483 | 1.00 | KDM4E (0.83) | KDM4EHTR7ADRB2ADRB1ALDH1A1 | |
| SCHEMBL11019742 | 1.00 | KDM4E (0.83) | KDM4EHTR7ADRB2ADRB1ALDH1A1 | |
| SCHEMBL11018654 | 1.00 | KDM4E (0.83) | KDM4EHTR7ADRB2ADRB1ALDH1A1 | |
| SCHEMBL11018444 | 1.00 | KDM4E (0.83) | KDM4EHTR7ADRB2ADRB1ALDH1A1 | |
| SCHEMBL11023742 | 0.98 | KDM4E (0.86) | KDM4EHTR7ADRB2ADRB1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11622980 | 0.97 | KDM4E (0.83) | KDM4EHTR7ADRB2ADRB1ALDH1A1 | |
| SCHEMBL8415073 | 0.93 | HTR7 (0.84) | KDM4EHTR7ADRB2ADRB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |