SCHEMBL11022294

SCHEMBL11022294

CCCC(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
RAB9A P51151 1/20 0.53
LIPE Q05469 13/20 0.52
BCHE P06276 1/20 0.48
MAPT P10636 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
MAPK1 P28482 1/20 0.48
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5174070 0.92 LMNA (0.53) LMNARAB9ALIPEBCHEMAPT
SCHEMBL988340 0.92 LMNA (0.53) LMNARAB9ALIPEBCHEMAPT
SCHEMBL7191647 0.92 LMNA (0.53) LMNARAB9ALIPEBCHEMAPT
SCHEMBL11241416 0.89 LMNA (0.55) LMNARAB9ALIPEBCHEMAPT
SCHEMBL619783 0.85 PPARG (0.59) PPARGPPARA
Fluazifop SCHEMBL16593831 0.83 LMNA (0.57) LMNARAB9ALIPEBCHEMAPT
SCHEMBL10742683 0.83 LMNA (0.52) LMNARAB9ALIPEBCHEMAPT
Fluazifop SCHEMBL1559717 0.82 LMNA (0.62) LMNARAB9ALIPEBCHEMAPT
Fluazifop-P SCHEMBL118853 0.82 LMNA (0.62) LMNARAB9ALIPEBCHEMAPT
Fluazifop SCHEMBL29370478 0.82 LMNA (0.62) LMNARAB9ALIPEBCHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0146238-A1 Synergistic herbicidal composition STAUFFER CHEMICAL COMPANY (US) 1985-06-26 EP claimed