Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022677 | 1.00 | MAPT (0.43) | MAPTMAPK1CYP1A2CYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL11020300 | 0.99 | TBXAS1 (0.44) | MAPTMAPK1CYP1A2CYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL11020295 | 0.99 | TBXAS1 (0.44) | MAPTMAPK1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10968079 | 0.87 | MAPT (0.44) | MAPTMAPK1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11021230 | 0.87 | MAPT (0.44) | MAPTMAPK1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11021227 | 0.87 | MAPT (0.44) | MAPTMAPK1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9549805 | 0.87 | MAPT (0.44) | MAPTMAPK1CYP1A2CYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL11021082 | 0.86 | TBXAS1 (0.45) | MAPTMAPK1CYP1A2CYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL11021095 | 0.86 | TBXAS1 (0.45) | MAPTMAPK1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11022827 | 0.86 | MAPK1 (0.43) | MAPTMAPK1CYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153678-A1 | Cinnamic acid derivatives, processes for the preparation thereof and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1985-09-04 | — | — | EP | disclosed |