Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116517 | 0.70 | TSHR (0.40) | LCKTSHRCDC7PARP1ALDH1A1 | |
| SCHEMBL17479085 | 0.68 | MEN1 (0.41) | MEN1KMT2AL3MBTL1LCKTSHR | |
| SCHEMBL28413209 | 0.67 | LCK (0.39) | LCKTSHRCDC7PARP1ALDH1A1 | |
| SCHEMBL11025580 | 0.67 | LCK (0.39) | LCKTSHRCDC7PARP1ALDH1A1 | |
| SCHEMBL3637941 | 0.66 | CA12 (0.62) | MEN1KMT2AL3MBTL1SLC40A1ALDH1A1 | |
| SCHEMBL29642968 | 0.66 | CA12 (0.62) | MEN1KMT2AL3MBTL1SLC40A1ALDH1A1 | |
| SCHEMBL29790728 | 0.66 | KMT2A (0.36) | MEN1KMT2AL3MBTL1LCKTSHR | |
| SCHEMBL2363489 | 0.62 | LCK (0.78) | KMT2ALCKTSHRPARP1ALDH1A1 | |
| SCHEMBL16418248 | 0.62 | CA1 (0.53) | MEN1KMT2AL3MBTL1LCKTSHR | |
| SCHEMBL12235480 | 0.61 | GRIN2D (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60156680-A | — | — | None | — | — | JP | disclosed |
| JP-S60156680-A | 7-CARBAMOYL-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1985-08-16 | — | — | JP | disclosed |