Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237042 | 0.85 | KDM4E (0.37) | SMN1; SMN2KDM4EALDH1A1HSD17B10KDM4B | |
| SCHEMBL9995940 | 0.71 | TSHR (0.37) | LCKCDC7PARP1SMN1; SMN2KDM4E | |
| SCHEMBL2116517 | 0.68 | TSHR (0.40) | LCKCDC7PARP1SMN1; SMN2KDM4E | |
| SCHEMBL11022720 | 0.67 | MEN1 (0.39) | LCKCDC7PARP1SMN1; SMN2KDM4E | |
| SCHEMBL2357761 | 0.66 | LCK (0.36) | LCKPARP1SMN1; SMN2KDM4EBRD4 | |
| SCHEMBL28413209 | 0.65 | LCK (0.39) | LCKCDC7PARP1SMN1; SMN2KDM4E | |
| SCHEMBL2363489 | 0.64 | LCK (0.78) | LCKPARP1SMN1; SMN2KDM4EBRD4 | |
| SCHEMBL3352053 | 0.63 | KDM1A (0.39) | LCKPARP1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30935786 | 0.62 | LCK (0.75) | LCKPARP1SMN1; SMN2KDM4EBRD4 | |
| SCHEMBL4405181 | 0.62 | LCK (0.75) | LCKPARP1SMN1; SMN2KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60156680-A | — | — | None | — | — | JP | disclosed |
| JP-S60156680-A | 7-CARBAMOYL-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1985-08-16 | — | — | JP | disclosed |