Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209069 | 1.00 | TDP1 (0.56) | TDP1CYP19A1NFE2L2TSHRSMN1; SMN2 | |
| SCHEMBL10975921 | 0.90 | TDP1 (0.69) | TDP1CYP19A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL10975917 | 0.90 | TDP1 (0.69) | TDP1CYP19A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL27261979 | 0.87 | NFE2L2 (0.50) | TDP1CYP19A1NFE2L2TSHRSMN1; SMN2 | |
| SCHEMBL29594574 | 0.86 | MAPT (0.66) | TDP1CYP19A1NFE2L2SMN1; SMN2MAPT | |
| SCHEMBL1578978 | 0.86 | MAPT (0.66) | TDP1CYP19A1NFE2L2SMN1; SMN2MAPT | |
| SCHEMBL1578983 | 0.86 | MAPT (0.66) | TDP1CYP19A1NFE2L2SMN1; SMN2MAPT | |
| SCHEMBL5442818 | 0.86 | MAPT (0.66) | TDP1CYP19A1NFE2L2SMN1; SMN2MAPT | |
| SCHEMBL11307656 | 0.83 | CYP19A1 (0.65) | CYP19A1NFE2L2SMN1; SMN2MAPTMAOB | |
| SCHEMBL29809086 | 0.83 | CYP19A1 (0.65) | CYP19A1NFE2L2SMN1; SMN2MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536599-A | HYDROLYZING THE NITRILE DERIVATIVE TO THE AMIDE USING AN ORGANIC QUATERNARY AMINE SALT CATALYST; EFFICIENCY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0041043-B1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF ALKENYL BENZENE OR ALKENYL NAPHTHALENE | CIBA-GEIGY AG (CH) | 1983-11-09 | — | — | EP | disclosed |
| EP-0008532-B1 | SYNTHESIS OF AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-07-20 | — | — | EP | disclosed |
| US-4335055-A | Process for the preparation of alkenylbenzene derivatives or alkenylnaphthalene derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| EP-0008532-A1 | Synthesis of amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-03-05 | — | — | EP | disclosed |