SCHEMBL11022809

SCHEMBL11022809

O=C1CSC(=S)N1CCCS(=O)(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.57
KMT2A Q03164 7/20 0.57
GAA P10253 4/20 0.57
GSK3A P49840 8/20 0.50
GSK3B P49841 8/20 0.50
ALDH1A1 P00352 6/20 0.49
MAPT P10636 5/20 0.41
POLB P06746 4/20 0.41
RECQL P46063 4/20 0.41
TDP1 Q9NUW8 4/20 0.41
THRB P10828 2/20 0.41
HTT P42858 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
PAX8 Q06710 1/20 0.40
MMP13 P45452 3/20 0.39
MAPK1 P28482 2/20 0.39
ALPG P10696 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 3/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11023531 0.95 MEN1 (0.60) MEN1KMT2AGAAGSK3AGSK3B
SCHEMBL11037601 0.94 MEN1 (0.62) MEN1KMT2AGAAGSK3AGSK3B
SCHEMBL4411450 0.90 GSK3A (0.53) MEN1KMT2AGAAGSK3AGSK3B
SCHEMBL6790202 0.80 GSK3A (0.56) MEN1KMT2AGAAGSK3AGSK3B
SCHEMBL3062340 0.78 GSK3A (0.62) MEN1KMT2AGAAGSK3AGSK3B
SCHEMBL4579359 0.75 GSK3A (0.59) MEN1KMT2AGAAGSK3AGSK3B
SCHEMBL11024577 0.74 MEN1 (0.97) MEN1KMT2AGAAGSK3AGSK3B
SCHEMBL8973113 0.74 MEN1 (0.46) MEN1KMT2AGAAGSK3AGSK3B
SCHEMBL16274020 0.73 MEN1 (0.65) MEN1KMT2AGAAGSK3AGSK3B
SCHEMBL14850663 0.73 MEN1 (0.65) MEN1KMT2AGAAGSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0048834-B1 METHOD FOR MEASUREMENT OF TRACE ENZYMES FUJI PHOTO FILM CO., LTD. (JP) 1985-06-19 EP disclosed
US-4414325-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1983-11-08 US disclosed
US-4356244-A Quinoxaline cyanine dye sensitized organic electron donor compounds MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-10-26 US disclosed
US-4337305-A INDOLE CYANINE DYES HAVING PHENYLSULFONYL OR BENZOYL GROUPS; LIGHT SENSITIVE ELEMENTS; ELECTROGRAPHY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-06-29 US disclosed
EP-0048834-A1 Method for measurement of trace enzymes FUJI PHOTO FILM CO., LTD. (JP) 1982-04-07 EP disclosed
US-4110116-A Fogged direct positive silver halide emulsion containing a cyanine dye having at least one benzoxazole or benzothiazole nucleus substituted with halogen atoms MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-08-29 US disclosed
US-4080496-A SENSITIZERS EASTMAN KODAK COMPANY (US) 1978-03-21 US disclosed
US-4075017-A Photothermographic material containing a combination of energy-sensitive organic dyes and process of forming a positive or negative image with the material EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-4030932-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1977-06-21 US disclosed
US-4026884-A SPECTRAL SENSITIZERS FOR SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1977-05-31 US disclosed
US-4025349-A Silver halide photographic elements spectrally sensitized with an acetylenic analog of cyanine or merocyanine dyes EASTMAN KODAK COMPANY (US) 1977-05-24 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed
US-4007170-A SILVER HALIDE SENSITIZERS EASTMAN KODAK COMPANY (US) 1977-02-08 US disclosed
US-4002480-A CONTAINING A DINUCLEAR MEROCYANINE SENSITIZING DYE AND AN ANTIFOGGING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1977-01-11 US disclosed
US-3976661-A SENSITIZERS, FILTERS EASTMAN KODAK COMPANY (US) 1976-08-24 US disclosed
US-3951666-A CYANINE AND MEROCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-20 US disclosed
US-3943142-A Dye intermediates and their preparation and use in the synthesis of methine dyes EASTMAN KODAK COMPANY (US) 1976-03-09 US disclosed
US-3936308-A Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed
US-3935010-A IMIDAZOQUINOXALINE DESENSITIZER EASTMAN KODAK COMPANY (US) 1976-01-27 US disclosed