Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 8/20 | 0.59 |
| ▸ | GSK3B | P49841 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | RECQL | P46063 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062340 | 0.87 | GSK3A (0.62) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL367565 | 0.83 | — | — | |
| SCHEMBL16636652 | 0.80 | GSK3A (0.56) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL3138532 | 0.80 | GSK3A (0.56) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL1279204 | 0.79 | MEN1 (0.77) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL1693423 | 0.79 | MAPT (0.56) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL4411450 | 0.78 | GSK3A (0.53) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL17445529 | 0.78 | MEN1 (0.60) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL2788487 | 0.77 | MEN1 (0.59) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL3085058 | 0.77 | KMT2A (0.88) | GSK3AGSK3BMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649231-B2 | Compound as mTOR inhibitor and use thereof | MEDICINAL BIOCONVERGENCE RESEARCH CENTER (KR) | 2023-05-16 | — | — | US | disclosed |
| CN-113980858-A | Lactobacillus plantarum YL399 for producing high-activity tannase and application thereof in preparation of codonopsis pilosula fermented feed | 上海植酵盛生物科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| US-20210292314-A1 | NOVEL COMPOUND AS mTOR INHIBITOR AND USE THEREOF | MEDICINAL BIOCONVERGENCE RESEARCH CENTER (KR) | 2021-09-23 | — | — | US | disclosed |
| EP-3786163-A1 | NOVEL COMPOUND AS MTOR INHIBITOR AND USE THEREOF | Medicinal Bioconvergence Research Center (KR) | 2021-03-03 | — | — | EP | disclosed |
| CN-112368279-A | Novel compounds as mTOR inhibitors and uses thereof | 医药生命融合研究团 | 2021-02-12 | — | — | CN | disclosed |
| CN-1932644-B | Method for producing sensitized dye and photosensitive composition given by using the same | FUJI PHOTO FILM CO LTD | 2010-05-12 | — | — | CN | disclosed |
| CN-101661223-A | Photomask blank and photomask | FUJI PHOTO FILM CO LTD | 2010-03-03 | — | — | CN | disclosed |
| CN-100545751-C | Photosensitive planographic plate | FUJI PHOTO FILM CO LTD (JP) | 2009-09-30 | — | — | CN | disclosed |
| CN-101526734-A | Photo mask material, photo mask and photo mask preparing method | FUJI PHOTO FILM CO LTD (JP) | 2009-09-09 | — | — | CN | disclosed |
| EP-1688466-B1 | Ink composition, ink jet recording method, printed material, method of producing planographic printing plate, and planographic printing plate | FUJIFILM CORP (JP) | 2008-11-26 | — | — | EP | disclosed |
| WO-1996022772-A1 | METHOD FOR TREATING MULTIPLE SCLEROSIS | ELI LILLY AND COMPANY (US) | 1996-08-01 | — | — | WO | disclosed |
| EP-0722729-A2 | Aryl-substituted rhodanines for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |
| EP-0391644-B1 | Aryl-substituted rhodanine derivatives | LILLY CO ELI (US) | 1996-06-19 | — | — | EP | disclosed |
| US-5356917-A | Antiischemic, antiinflammatory, antiarthritic agents, treat-ment of dystrophic mammals | ELI LILLY AND COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0359431-B1 | Halomethyl-1,3,5-triazines containing a sensitizer moiety | MINNESOTA MINING & MFG (US) | 1993-12-22 | — | — | EP | disclosed |
| US-5158966-A | Aryl-substituted rhodanine derivatives | THE UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0500337-A1 | Composition containing aryl-substituted rhodanine derivatives for the treatment of type I diabetes | UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1992-08-26 | — | — | EP | disclosed |
| US-4977076-A | FLEXIBLE SUPPORT WITH SILVER HALIDE LIGHT SENSITIVE LAYER CONTAINING CYANINE DYE SENSITIZING AT SPECIFIC WAVELENGTHS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0391644-A2 | Aryl-substituted rhodanine derivatives | ELI LILLY AND COMPANY (US) | 1990-10-10 | — | — | EP | disclosed |
| EP-0359431-A2 | Halomethyl-1,3,5-triazines containing a sensitizer moiety | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649231-B2 | Compound as mTOR inhibitor and use thereof | MTOR, RICTOR, RPTOR | GSK3A 103/4885GSK3B 75/4885MEN1 855/4885 |
| US-20210292314-A1 | NOVEL COMPOUND AS mTOR INHIBITOR AND USE THEREOF | MTOR, RICTOR, RPTOR | GSK3A 143/4885GSK3B 110/4885MEN1 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.