Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL622425 | 0.88 | EGFR (0.42) | EGFRSRCKDRF7F3 | |
| Adenine SCHEMBL22748483 | 0.88 | F7 (0.56) | EGFRSRCKDRF7F3 | |
| Adenine SCHEMBL15699 | 0.88 | F7 (0.56) | EGFRSRCKDRF7F3 | |
| Adenine SCHEMBL2564207 | 0.88 | F7 (0.56) | EGFRSRCKDRF7F3 | |
| Adenine SCHEMBL23859925 | 0.87 | F7 (0.55) | EGFRSRCKDRF7F3 | |
| Adenine SCHEMBL7712105 | 0.87 | F7 (0.55) | EGFRSRCKDRF7F3 | |
| Adenine SCHEMBL22129922 | 0.87 | F7 (0.55) | EGFRSRCKDRF7F3 | |
| Adenine SCHEMBL28614873 | 0.87 | F7 (0.55) | EGFRSRCKDRF7F3 | |
| Adenine SCHEMBL23531099 | 0.87 | F7 (0.55) | EGFRSRCKDRF7F3 | |
| Adenine SCHEMBL11807677 | 0.87 | F7 (0.55) | EGFRSRCKDRF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906639-B2 | Method of determining factor XIII with the aid of plasma-based reference material | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2014-12-09 | — | — | US | disclosed |
| US-20120190052-A1 | Method of determining factor XIII by means of NAD(P)H-analogues | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2012-07-26 | — | — | US | disclosed |
| US-20120190053-A1 | Method of determining factor XIII with the aid of plasma-based reference material | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2012-07-26 | — | — | US | disclosed |