Adenine

Adenine

SCHEMBL622425

NC(=S)c1cccnc1.Nc1ncnc2[nH]cnc12

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 1/20 0.42
▸ SRC P12931 1/20 0.42
▸ KDR P35968 1/20 0.42
▸ F7 P08709 1/20 0.39
▸ F3 P13726 1/20 0.39
▸ SARM1 Q6SZW1 1/20 0.39
▸ SIRT2 Q8IXJ6 1/20 0.39
▸ SIRT6 Q8N6T7 1/20 0.39
▸ SIRT1 Q96EB6 1/20 0.39
▸ SIRT3 Q9NTG7 1/20 0.39
▸ SIRT5 Q9NXA8 1/20 0.39
▸ SIRT4 Q9Y6E7 1/20 0.39
▸ PI4KA P42356 1/20 0.39
▸ PI4K2B Q8TCG2 1/20 0.39
▸ PI4K2A Q9BTU6 1/20 0.39
▸ PI4KB Q9UBF8 1/20 0.39
▸ POLB P06746 1/20 0.38
▸ MAP4K4 O95819 1/20 0.38
▸ CTSL P07711 1/20 0.34
▸ HDAC1 Q13547 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL22828945 0.94 EGFR (0.41) EGFRSRCKDRF7F3
Adenine SCHEMBL11022893 0.88 EGFR (0.43) EGFRSRCKDRF7F3
Adenine SCHEMBL22748483 0.87 F7 (0.56) EGFRSRCKDRF7F3
Adenine SCHEMBL2564207 0.87 F7 (0.56) EGFRSRCKDRF7F3
Adenine SCHEMBL15699 0.87 F7 (0.56) EGFRSRCKDRF7F3
Adenine SCHEMBL23531099 0.86 F7 (0.55) EGFRSRCKDRF7F3
Adenine SCHEMBL22129922 0.86 F7 (0.55) EGFRSRCKDRF7F3
Adenine SCHEMBL11807677 0.86 F7 (0.55) EGFRSRCKDRF7F3
Adenine SCHEMBL7712105 0.86 F7 (0.55) EGFRSRCKDRF7F3
Adenine SCHEMBL23859925 0.86 F7 (0.55) EGFRSRCKDRF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114521617-B Feed additive for preventing pig diarrhea and preparation method thereof 江苏农牧科技职业学院 2023-11-07 — — CN claimed
CN-114521617-A Feed additive for preventing pig diarrhea and preparation method thereof 江苏农牧科技职业学院 2022-05-24 — — CN claimed
CN-107075558-B Novel assay methods and compositions using kinases 旭化成制药株式会社 2021-09-24 — — CN claimed
US-10975411-B2 Method and reagent for measuring mevalonic acid, 3-hydroxymethylglutaryl coenzyme A, and coenzyme A ASAHI KASEI PHARMA CORPORATION (JP) 2021-04-13 — — US claimed
EP-3199639-B1 NOVEL MEASUREMENT METHOD USING KINASE, AND COMPOSITION ASAHI KASEI PHARMA CORP (JP) 2020-12-30 — — EP claimed
CN-111575339-A 1, 5-anhydroglucitol enzymatic quantitative method and reagent therefor 王学忠 2020-08-25 — — CN claimed
US-10472665-B2 Measuring method and composition using kinase ASAHI KASEI PHARMA CORPORATION (JP) 2019-11-12 — — US claimed
US-20170306389-A1 NOVEL MEASURING METHOD AND COMPOSITION USING KINASE ASAHI KASEI PHARMA CORPORATION (JP) 2017-10-26 — — US claimed
EP-3199639-A1 NOVEL MEASUREMENT METHOD USING KINASE, AND COMPOSITION Asahi Kasei Pharma Corporation (JP) 2017-08-02 — — EP claimed
WO-2017114796-A1 ADENOSYLHOMOCYSTEINASE BINDING SUBSTANCES FOR MEDICAL USE LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2017-07-06 — — WO claimed
EP-0639646-A1 HIGH PRECISION DETERMINATION OF D-GLUCOSE-6-PHOSPHATE AND COMPOSITION THEREFOR ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1995-02-22 — — EP claimed
US-5385829-A Method of assaying for acyl-L-carnitines and short-chain acyl-carnitines ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1995-01-31 — — US claimed
EP-0632133-A1 HIGHLY SENSITIVE DETERMINATION OF D-3-HYDROXYBUTYRIC ACID OR ACETOACETIC ACID AND COMPOSITION THEREFOR Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1995-01-04 — — EP claimed
US-5356790-A Highly sensitive assay method for myo-inositol, composition for practicing same, novel myo-inositol dehydrogenase, and process for producing same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-10-18 — — US claimed
EP-0575610-A1 HIGHLY SENSITIVE DETERMINATION OF AMMONIA, $g(alpha)-AMINO ACID OR $g(alpha)-KETO ACID AND COMPOSITION THEREFOR TOYO JOZO CO., LTD. (JP) 1993-12-29 — — EP claimed
US-5266463-A Highly sensitive assay method for L-carnitine and composition for practicing same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-11-30 — — US claimed
EP-0533940-A1 CRYSTALLINE POTASSIUM THIONICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE AND PRODUCTION THEREOF ORIENTAL YEAST CO., LTD. (JP) 1993-03-31 — — EP claimed
EP-0477001-A2 Highly sensitive assay method for myo-inositol and composition for practicing same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1992-03-25 — — EP claimed
EP-0437373-A1 High sensitive assay method of L-carnitine and composition for an assay ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1991-07-17 — — EP claimed
EP-0387697-A2 Determination of aminotranferases ABBOTT LABORATORIES (US) 1990-09-19 — — EP claimed
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