Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10527237 | 1.00 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10527602 | 1.00 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11022117 | 1.00 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11022440 | 1.00 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11019210 | 1.00 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11021192 | 1.00 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11017799 | 1.00 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10525636 | 0.98 | RAB9A (0.60) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11021376 | 0.97 | RAB9A (0.56) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11019595 | 0.94 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |