Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30694750 | 0.98 | GRIA1 (0.40) | ESR1AKR1B10AKR1B1MAOBPTGS2 | |
| SCHEMBL9440460 | 0.97 | GRIA1 (0.39) | ESR1AKR1B10AKR1B1MAOBPTGS2 | |
| SCHEMBL29176161 | 0.83 | PRMT1 (0.50) | PAOXKDM4EALDH1A1S1PR1S1PR3 | |
| SCHEMBL11032133 | 0.83 | PRMT1 (0.50) | PAOXKDM4EALDH1A1S1PR1S1PR3 | |
| SCHEMBL28520466 | 0.82 | PRMT1 (0.49) | PAOXKDM4EALDH1A1S1PR1S1PR3 | |
| SCHEMBL30694747 | 0.82 | PRMT1 (0.49) | PAOXKDM4EALDH1A1S1PR1S1PR3 | |
| SCHEMBL30423565 | 0.82 | ESR1 (0.36) | ESR1AKR1B10AKR1B1MAOBPTGS2 | |
| SCHEMBL30664480 | 0.81 | ESR1 (0.42) | ESR1AKR1B10AKR1B1MAOBPTGS2 | |
| SCHEMBL8756586 | 0.76 | APP (0.44) | ESR1AKR1B10AKR1B1MAOBPTGS2 | |
| SCHEMBL8756509 | 0.76 | APP (0.44) | ESR1AKR1B10AKR1B1MAOBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097096-B1 | PROCESS FOR THE PREPARATION OF PHENOL AMIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1985-08-28 | — | — | EP | disclosed |
| EP-0097096-A1 | Process for the preparation of phenol amides | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1983-12-28 | — | — | EP | disclosed |
| WO-1983004411-A1 | METHOD FOR THE PREPARATION OF PHENOLAMIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1983-12-22 | — | — | WO | disclosed |