SCHEMBL29176161

SCHEMBL29176161

NCCCCNC/C=C/c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.50
RAB9A P51151 1/20 0.43
KDM4E B2RXH2 1/20 0.42
IDO1 P14902 2/20 0.42
ALDH1A1 P00352 1/20 0.41
S1PR1 P21453 3/20 0.41
S1PR3 Q99500 2/20 0.41
PAOX Q6QHF9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11032133 1.00 PRMT1 (0.50) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL28520466 0.98 PRMT1 (0.49) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL30694747 0.98 PRMT1 (0.49) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL4948645 0.91 PRMT1 (0.54) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL28725423 0.91 PRMT1 (0.54) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL11031807 0.83 HDAC3 (0.45) IDO1
SCHEMBL11023328 0.83 ESR1 (0.40) KDM4EALDH1A1S1PR1S1PR3PAOX
SCHEMBL11597360 0.83 PRMT1 (0.55) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL11597357 0.83 PRMT1 (0.55) PRMT1RAB9AKDM4EIDO1ALDH1A1
SCHEMBL11033807 0.83 EGFR (0.51) PRMT1RAB9AKDM4EALDH1A1S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114594171-B Metabolome deep annotation method 中国科学院大连化学物理研究所 2023-12-15 CN disclosed