Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GSDMD | P57764 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301838 | 0.95 | ALDH1A1 (0.33) | ALDH1A1HRH3ABCB11CYP2E1PTGS1 | |
| SCHEMBL17988372 | 0.91 | ALDH1A1 (0.31) | ALDH1A1HRH3ABCB11CYP2E1PTGS1 | |
| Hydrochloric Acid SCHEMBL14482126 | 0.91 | ALDH1A1 (0.31) | ALDH1A1HRH3ABCB11CYP2E1PTGS1 | |
| SCHEMBL11201562 | 0.81 | — | — | |
| SCHEMBL438016 | 0.75 | — | — | |
| SCHEMBL2607153 | 0.75 | — | — | |
| SCHEMBL1736341 | 0.75 | ALDH1A1 (0.40) | ALDH1A1HRH3HTT | |
| SCHEMBL30 | 0.75 | — | — | |
| SCHEMBL124190 | 0.75 | — | — | |
| SCHEMBL31066753 | 0.73 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153784-B2 | Imaging of enzyme activity | THE GENERAL HOSPITAL CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-7964682-B2 | Method for producing phosphoric acid ester-based polymer | KAO CORPORATION (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20090258969-A1 | Method for Producing Phosphoric Acid Ester-Based Polymer | KAO CORPORATION (JP) | 2009-10-15 | — | — | US | disclosed |
| US-20080044827-A1 | Imaging of Enzyme Activity | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080044827-A1 | Imaging of Enzyme Activity | GBA3, BCHE, MGAM | ALDH1A1 716/4885HRH3 3477/4885ABCB11 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.