Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14650407 | 0.80 | BCHE (0.47) | TAAR1TSHRCYP1A2CYP2D6NFKB1 | |
| SCHEMBL2998659 | 0.79 | TAAR1 (0.56) | TAAR1TSHRCYP1A2CYP2D6NFKB1 | |
| SCHEMBL21345586 | 0.78 | TAAR1 (0.50) | TAAR1SLC6A2HTR2ASIGMAR1ADRB2 | |
| SCHEMBL3056754 | 0.78 | TAAR1 (1.00) | TAAR1TSHRHTR2ALMNAIDO1 | |
| SCHEMBL25453155 | 0.77 | MPO (0.56) | TAAR1TSHRCYP2D6HSD17B10 | |
| SCHEMBL12312602 | 0.77 | TAAR1 (0.63) | TAAR1CYP1A2CYP2D6CYP2C19SLC6A2 | |
| SCHEMBL4852440 | 0.77 | TAAR1 (0.63) | TAAR1SLC6A2HTR2ALMNAIDO1 | |
| SCHEMBL5183864 | 0.77 | SLC6A2 (0.41) | TAAR1SLC6A2HTR2ASIGMAR1ADRB2 | |
| SCHEMBL11155402 | 0.77 | TAAR1 (0.48) | TAAR1CYP1A2CYP2D6CYP2C19SLC6A2 | |
| SCHEMBL30878491 | 0.75 | TAAR1 (0.56) | TAAR1CYP1A2CYP2D6CYP2C19ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163948-A1 | Process for producing an indoline | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |