SCHEMBL11023403

SCHEMBL11023403

O=C(O)c1ccccc1CON[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MME P08473 4/20 0.46
ACE P12821 4/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
FOLH1 Q04609 2/20 0.43
NAALAD2 Q9Y3Q0 1/20 0.43
ITGB1 P05556 2/20 0.42
ITGA4 P13612 2/20 0.42
ITGB7 P26010 2/20 0.42
PPARG P37231 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28216930 0.84 MME (0.56) MMEACEFOLH1NAALAD2PPARG
SCHEMBL29664067 0.84 MME (0.56) MMEACEFOLH1NAALAD2PPARG
SCHEMBL7211707 0.77 MME (0.51) MMENAALAD2PPARG
SCHEMBL6130478 0.77 MME (0.51) MMENAALAD2PPARG
SCHEMBL6130477 0.77 MME (0.51) MMENAALAD2PPARG
SCHEMBL475962 0.76 FOLH1 (0.54) MMEACEMEN1KMT2AL3MBTL1
SCHEMBL475961 0.76 FOLH1 (0.54) MMEACEMEN1KMT2AL3MBTL1
SCHEMBL6152838 0.76 MMP2 (0.45) ACEFOLH1
SCHEMBL5840486 0.76 MMP2 (0.45) ACEFOLH1
SCHEMBL8664220 0.76 MMP2 (0.45) ACEFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034052-B1 A RECORDING MEDIUM PROCESS SHIZAI CO. LTD. (JP) 1985-05-08 EP disclosed