Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Triphenylmethanamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 6/20 | 0.93 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphenylmethanamine SCHEMBL115149 | 0.97 | KCNN4 (1.00) | KCNN4TSHRALDH1A1TAAR1MAPK1 | |
| Triphenylmethanamine SCHEMBL1508115 | 0.93 | KCNN4 (0.93) | KCNN4TSHRALDH1A1TAAR1MAPK1 | |
| Triphenylmethanamine SCHEMBL3317188 | 0.93 | KCNN4 (0.93) | KCNN4TSHRALDH1A1TAAR1MAPK1 | |
| Triphenylmethanamine SCHEMBL1508351 | 0.93 | KCNN4 (0.93) | KCNN4TSHRALDH1A1TAAR1MAPK1 | |
| Triphenylmethanamine SCHEMBL1508398 | 0.93 | KCNN4 (0.93) | KCNN4TSHRALDH1A1TAAR1MAPK1 | |
| Triphenylmethanamine SCHEMBL7661114 | 0.93 | KCNN4 (0.93) | KCNN4TSHRALDH1A1TAAR1MAPK1 | |
| Triphenylmethanamine SCHEMBL31146599 | 0.93 | KCNN4 (0.93) | KCNN4TSHRALDH1A1TAAR1MAPK1 | |
| Triphenylmethanamine SCHEMBL27516266 | 0.90 | KCNN4 (0.88) | KCNN4TSHRALDH1A1TAAR1MAPK1 | |
| Triphenylmethanamine SCHEMBL2634623 | 0.88 | KCNN4 (0.82) | KCNN4TSHRALDH1A1TAAR1MAPK1 | |
| Triphenylmethanamine SCHEMBL8754948 | 0.85 | KCNN4 (0.78) | KCNN4TSHRALDH1A1TAAR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119505867-A | Gold nanocluster and application thereof in organophosphorus pesticide residue detection | 河南省农业科学院农产品质量安全研究所 | 2025-02-25 | — | — | CN | claimed |
| CN-119505867-A | Gold nanocluster and application thereof in organophosphorus pesticide residue detection | 河南省农业科学院农产品质量安全研究所 | 2025-02-25 | — | — | CN | disclosed |
| EP-0012819-B1 | METHOD FOR FORMING A FILM ADHERING TO A SUBSTRATE AND METHOD FOR WRITING AND ERASING INFORMATION IN A FILM THUS PREPARED | International Business Machines Corporation (US) | 1985-06-12 | — | — | EP | disclosed |
| US-4264693-A | HEAVY METAL IODIDES, CATALYSTS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1981-04-28 | — | — | US | disclosed |
| EP-0012819-A2 | Method for forming a film adhering to a substrate and method for writing and erasing information in a film thus prepared | International Business Machines Corporation (US) | 1980-07-09 | — | — | EP | disclosed |