Triphenylmethanamine

Triphenylmethanamine

SCHEMBL1508115

F.NC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.93
TSHR P16473 2/20 0.45
ALDH1A1 P00352 1/20 0.45
TAAR1 Q96RJ0 1/20 0.42
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPK1 P28482 1/20 0.39
KIF11 P52732 4/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphenylmethanamine SCHEMBL115149 0.97 KCNN4 (1.00) KCNN4TSHRALDH1A1TAAR1CYP1A2
Triphenylmethanamine SCHEMBL3317188 0.93 KCNN4 (0.93) KCNN4TSHRALDH1A1TAAR1CYP1A2
Triphenylmethanamine SCHEMBL1508351 0.93 KCNN4 (0.93) KCNN4TSHRALDH1A1TAAR1CYP1A2
Triphenylmethanamine SCHEMBL31146599 0.93 KCNN4 (0.93) KCNN4TSHRALDH1A1TAAR1CYP1A2
Triphenylmethanamine SCHEMBL1508398 0.93 KCNN4 (0.93) KCNN4TSHRALDH1A1TAAR1CYP1A2
Triphenylmethanamine SCHEMBL7661114 0.93 KCNN4 (0.93) KCNN4TSHRALDH1A1TAAR1CYP1A2
Triphenylmethanamine SCHEMBL11023487 0.93 KCNN4 (0.93) KCNN4TSHRALDH1A1TAAR1CYP1A2
Triphenylmethanamine SCHEMBL27516266 0.90 KCNN4 (0.88) KCNN4TSHRALDH1A1TAAR1CYP1A2
Triphenylmethanamine SCHEMBL2634623 0.88 KCNN4 (0.82) KCNN4TSHRALDH1A1TAAR1CYP1A2
Triphenylmethanamine SCHEMBL8754693 0.85 KCNN4 (0.78) KCNN4TSHRALDH1A1TAAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206673-B2 Method of preparing boron-nitrogen compounds WILDCAT DISCOVERY TECHNOLOGIES (US) 2012-06-26 US disclosed
US-20110064640-A1 METHOD OF PREPARING BORON-NITROGEN COMPOUNDS WILDCAT DISCOVERY TECHNOLOGIES (US) 2011-03-17 US disclosed
EP-0269884-B1 CATALYZED ALKYLATION OF HALOPYRIDINATES IN THE ABSENCE OF ADDED ORGANIC SOLVENTS DOWELANCO (US) 1991-09-25 EP disclosed
EP-0277292-B1 ORGANIC SOLVENT-FREE PROCESS FOR PREPARING PYRIMIDINYL ORGANOPHOSPHATES THE DOW CHEMICAL COMPANY (US) 1991-05-08 EP disclosed
EP-0277292-A1 Organic solvent-free process for preparing pyrimidinyl organophosphates THE DOW CHEMICAL COMPANY (US) 1988-08-10 EP disclosed
EP-0269884-A1 Catalyzed alkylation of halopyridinates in the absence of added organic solvents DOWELANCO (US) 1988-06-08 EP disclosed
US-4701531-A Catalyzed alkylation of halopyridinates in the absence of added organic solvents THE DOW CHEMICAL COMPANY (US) 1987-10-20 US disclosed
US-4546189-A Preparation of cyano(6-(substituted phenoxy)-2-pyridinyl)methyl esters of 3-(2,2-dihaloethenyl)-2,2-dimethylcyclopropane carboxylic acids THE DOW CHEMICAL COMPANY (US) 1985-10-08 US disclosed
EP-0010891-B1 HETEROCYCLIC SUBSTITUTED TRIAZOLYL PHOSPHOROUS COMPOUNDS, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHOD FOR CONTROLLING INSECTS THE DOW CHEMICAL COMPANY (US) 1982-09-01 EP disclosed
EP-0050846-A1 Preparation of cyano (6-(substituted phenoxy)-2-pyridinyl) methyl esters of 3-(2,2-dihaloethenyl)-2,2-dimethyl cyclopropane carboxylic acids THE DOW CHEMICAL COMPANY (US) 1982-05-05 EP disclosed
US-4061682-A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT THE DOW CHEMICAL COMPANY (US) 1977-12-06 US disclosed
US-4028439-A QUATERNARY AMMONIUM SALT AND IMIDAZOLE CATALYSTS THE DOW CHEMICAL COMPANY (US) 1977-06-07 US disclosed
US-4016225-A WITH QUATERNARY AMMONIUM SALT AND 1,4-DIAZABICYCLO(2.2.2)OCTANE CATALYST THE DOW CHEMICAL COMPANY (US) 1977-04-05 US disclosed
US-4014891-A FROM AN ALKALI METAL ARYL MERCAPTIDE AND BROMOCHLOROMETHANE IN A QUATERNARY AMMONIUM SALT THE DOW CHEMICAL COMPANY (US) 1977-03-29 US disclosed
US-4007197-A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT AND TERTIARY AMINE CATALYST THE DOW CHEMICAL COMPANY (US) 1977-02-08 US disclosed
US-4001293-A Process for production of γ-halonitriles THE DOW CHEMICAL COMPANY (US) 1977-01-04 US disclosed
US-3996259-A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT THE DOW CHEMICAL COMPANY (US) 1976-12-07 US disclosed
US-3974199-A Process for production of cyclopropylcyanide THE DOW CHEMICAL COMPANY (US) 1976-08-10 US disclosed
US-3972887-A QUATERNARY AMMONIUM SALT CATALYST THE DOW CHEMICAL COMPANY (US) 1976-08-03 US disclosed
US-3969360-A Catalyzed alkylation of halopyridinates THE DOW CHEMICAL COMPANY (US) 1976-07-13 US disclosed