SCHEMBL1102370

SCHEMBL1102370

Cc1ccc(-c2c3cc(-c4sc(C)cc4C)sc3c(-c3ccc(C)cc3)c3cc(-c4sc(C)cc4C)sc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
TYK2 P29597 1/20 0.33
JAK3 P52333 1/20 0.33
PTGS2 P35354 1/20 0.31
MAP3K8 P41279 1/20 0.31
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1102369 0.87 NPC1 (0.35) JAK2JAK1TYK2JAK3PTGS2
SCHEMBL1102375 0.84 ESR1 (0.37) ESR1ESR2
SCHEMBL2742927 0.81 JAK2 (0.43) ESR1ESR2JAK2JAK1TYK2
SCHEMBL18100476 0.81 NEK1 (0.35) ESR1ESR2JAK2JAK1TYK2
SCHEMBL1102374 0.81 NPC1 (0.31)
SCHEMBL15730462 0.75 PKM (0.31)
SCHEMBL14433393 0.72 ESR1 (0.49) ESR1ESR2MAP3K8
SCHEMBL15441409 0.72 ESR1 (0.45) ESR1ESR2
SCHEMBL15730461 0.72 ESR1 (0.32) ESR1ESR2
SCHEMBL17487322 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153755-B2 Electronic devices XEROX CORPORATION (US) 2012-04-10 US disclosed
US-20110034668-A1 ELECTRONIC DEVICES XEROX CORPORATION (US) 2011-02-10 US disclosed
US-7834132-B2 Electronic devices XEROX CORPORATION (US) 2010-11-16 US disclosed
US-7820782-B2 Poly(dithienylbenzo[1,2-b:4,5-b′]dithiophene) polymers XEROX CORPORATION (US) 2010-10-26 US disclosed
US-20080103286-A1 Poly(dithienylbenzo[1,2-B:4,5-B']dithiophene) polymers XEROX CORPORATION 2008-05-01 US disclosed
US-20080102559-A1 Electronic devices XEROX CORPORATION 2008-05-01 US disclosed