Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017816 | 0.86 | PDE3A (0.52) | KDM4EHPGDPDE3APDE4ABLM | |
| SCHEMBL11018954 | 0.86 | KDM4E (0.67) | KDM4EHPGDPDE3APDE4ABLM | |
| SCHEMBL11019985 | 0.85 | PDE3A (0.70) | KDM4EHPGDPDE3APDE4ABLM | |
| SCHEMBL5480537 | 0.83 | KDM4E (0.69) | KDM4EHPGDPDE3APDE4ABLM | |
| SCHEMBL11633622 | 0.81 | HPGD (0.53) | KDM4EHPGDALDH1A1GAASCN2A | |
| SCHEMBL11018440 | 0.80 | HPGD (0.56) | KDM4EHPGDPDE3APDE4ABLM | |
| SCHEMBL11018334 | 0.76 | KDM4E (0.53) | KDM4EHPGDPDE3APDE4ABLM | |
| SCHEMBL11020274 | 0.75 | MEN1 (0.65) | KDM4EHPGDPDE3APDE4ABLM | |
| SCHEMBL11021916 | 0.75 | KDM4E (0.49) | KDM4EHPGDPDE3APDE4ABLM | |
| SCHEMBL11020641 | 0.74 | PDE3A (0.53) | KDM4EHPGDPDE3APDE4ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |