Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 4/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045332 | 0.84 | TSHR (0.42) | EGLN1CA12CA1CA2CA9 | |
| SCHEMBL11022194 | 0.84 | EGLN1 (0.52) | EGLN1CA12CA1CA2CA9 | |
| SCHEMBL11024050 | 0.76 | FPR2 (0.38) | EGLN1CA12CA1CA2CA9 | |
| SCHEMBL491449 | 0.74 | TSHR (0.43) | CA12CA1CA2CA9TSHR | |
| SCHEMBL8680851 | 0.74 | TSHR (0.40) | CA12CA1CA2CA9TSHR | |
| SCHEMBL2028174 | 0.72 | TSHR (0.46) | TSHRTDP1PPARDMAPTNPC1 | |
| SCHEMBL5272432 | 0.72 | TSHR (0.41) | CA12CA1CA2CA9TSHR | |
| SCHEMBL21626325 | 0.71 | TSHR (0.38) | CA12CA1CA2CA9TSHR | |
| SCHEMBL30956298 | 0.71 | TSHR (0.38) | TSHRTDP1PPARDMAPTNPC1 | |
| SCHEMBL1723694 | 0.71 | MAPT (0.42) | EGLN1TSHRMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063411-B1 | SUBSTITUTED METHANEPHOSHONIC ACID DERIVATIVES, THEIR USE AS HERBICIDES, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR PREPARING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-05 | — | — | EP | disclosed |