FPR2

N-formyl peptide receptor 2 · P25090 · FPR2 on Sugi Atlas →

95,025 patent compounds predicted against FPR2, 43,991 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL560413	0.71	13/20
SCHEMBL560511	0.69	13/20
SCHEMBL561459	0.68	13/20
SCHEMBL560221	0.67	13/20
SCHEMBL560237	0.67	13/20
SCHEMBL560719	0.66	13/20
Cyclophenazine (SCHEMBL351628)	0.77	12/20
Cyclophenazine (SCHEMBL122920)	0.76	12/20
Fluphenazine Decanoate (SCHEMBL41288)	0.69	12/20
Fluphenazine Enanthate (SCHEMBL120793)	0.69	12/20
Duoperone (SCHEMBL121485)	0.64	12/20
Duoperone (SCHEMBL121486)	0.64	12/20
SCHEMBL466993	0.63	12/20
SCHEMBL590253	0.59	12/20
SCHEMBL590254	0.59	12/20
SCHEMBL590255	0.59	12/20
SCHEMBL590256	0.59	12/20
SCHEMBL589185	0.58	12/20
SCHEMBL589186	0.58	12/20
SCHEMBL589187	0.58	12/20

Clinical trials — most relevant to FPR2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion	PHASE4	COMPLETED
Efficacy of DEXamethasone in Patients With Acute Hypoxemic REspiratory Failure Caused by INfEctions	PHASE4	RECRUITING
Dupilumab for Prevention of Recurrence of CRSwNP After ESS	PHASE4	COMPLETED
Ramatroban/Montelukast Versus Montelukast/Placebo on the Early Allergic Reaction in Asthma Sensitive to House Dust Mite	PHASE2/PHASE3	WITHDRAWN
Montelukast for Early Life Wheezing	PHASE2/PHASE3	COMPLETED
Triamcinolone Versus Methylprednisolone in Transversus Abdominis Plane Block	PHASE2/PHASE3	COMPLETED
Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19	PHASE1/PHASE2	COMPLETED
Targeted Anticoagulation Therapy to Reduce Inflammation and Cellular Activation in Long-term HIV Disease	PHASE2	COMPLETED
Electrophilic Fatty Acid Derivatives in Asthma	PHASE1	COMPLETED
Serum sST2/ miR-223 as a Dual Biomarker for Disease Activity & Clinical Efficacy of SLIT in HDM-Induced Allergic Rhinitis	PHASE1	COMPLETED
Pro-Resolving Mediators in Acute Inflammation in Humans	EARLY_PHASE1	COMPLETED
Biomarkers in Participants With Hidradenitis Suppurativa Receiving Guselkumab.	EARLY_PHASE1	WITHDRAWN
The Severe Asthma Research Program III-Boston Clinical Site	nan	COMPLETED
NETs: Protection or Harm in Neonatal Inflammation or Infection	nan	RECRUITING
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation	nan	UNKNOWN
Neutrophil FFA2/GPR43 Receptor Expression in Patients With the Diagnosis of Sepsis	nan	WITHDRAWN
Aspirin and Neutrophils in Preeclampsia	nan	COMPLETED
Study of the Functional Status Neutrophils in Rheumatoid Arthritis Patients to Identify New Biomarkers of Response to Anti-TNFalpha Therapy	nan	UNKNOWN
In Vitro Studies on Pharmacological Regulation and Genetic Risk Factors of Peripheral Human Nociceptors	nan	COMPLETED
Role of Nox2 in CNI-induced Renal Fibrosis	nan	COMPLETED
PGE2/IL-22 Pathway in Various Forms of Eczema	nan	COMPLETED
Palmitoylethanolamide in Ulcerative Colitis	nan	NOT_YET_RECRUITING
Pathogenic Mechanisms in C Diff Infection and Colitis	nan	COMPLETED
Diagnostic and Translational Values of Point-of-care Blood Eosinophils and Exhaled Nitric Oxide (FeNO) in People Referred by Primary Care for Suspected Asthma	nan	COMPLETED
Lipid Mediators in Multiple Sclerosis	nan	COMPLETED
Evaluation of Serum Follistatin-Like Protein 1 Levels in Behcet's Disease and Its Association With Disease Activity	nan	COMPLETED
Assessment of Vitamin D Supplementation and Immune Function	nan	COMPLETED
Gluten-related Disorders in Familial Mediterranean Fever Patients	nan	COMPLETED
Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage Function	nan	COMPLETED
Potential Role of Inflammasome NLRP3 And IL-1B Gene Expression in COVID-19 Patients: Impact of Ferretin and D -Dimer.	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a FPR2 binder may also engage these)

Protein	Name	Similarity
P79242	—	1.000	P79242 →
P79190	—	1.000	P79190 →
P79236	—	1.000	P79236 →
P79235	—	1.000	P79235 →
P79177	—	1.000	P79177 →
O88536	—	1.000	O88536 →
P79189	—	1.000	P79189 →
Q05394	—	0.999	Q05394 →
P79241	—	0.999	P79241 →
P79176	—	0.999	P79176 →
P79243	—	0.999	P79243 →
P79237	—	0.999	P79237 →
P33766	—	0.998	P33766 →
Q3SXG2	—	0.998	Q3SXG2 →
P79240	—	0.997	P79240 →
O88537	—	0.997	O88537 →
P0C7U4	—	0.996	P0C7U4 →
P79178	—	0.996	P79178 →
P30993	—	0.996	P30993 →
FPR1	fMet-Leu-Phe receptor	0.996	landscape →
A4FUQ5	—	0.996	A4FUQ5 →
O08790	—	0.995	O08790 →
C5AR1	C5a anaphylatoxin chemotactic receptor 1	0.995	landscape →
FPR3	N-formyl peptide receptor 3	0.995	landscape →
P30992	—	0.994	P30992 →
P79175	—	0.994	P79175 →
P79191	—	0.994	P79191 →
Q71MR7	—	0.993	Q71MR7 →
Q49SP8	—	0.993	Q49SP8 →
Q49SQ2	—	0.992	Q49SQ2 →