Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 3/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023880 | 0.98 | METAP2 (0.44) | METAP2KDM5APHF8KDM2AKDM4C | |
| SCHEMBL11024609 | 0.98 | METAP2 (0.44) | METAP2KDM5APHF8KDM2AKDM4C | |
| SCHEMBL11020226 | 0.98 | METAP2 (0.44) | METAP2KDM5APHF8KDM2AKDM4C | |
| SCHEMBL11020724 | 0.98 | METAP2 (0.43) | METAP2KDM5APHF8KDM2AKDM4C | |
| SCHEMBL11020924 | 0.97 | METAP2 (0.45) | METAP2KDM5APHF8KDM2AKDM4C | |
| SCHEMBL11021832 | 0.94 | TP53 (0.42) | METAP2KDM5APHF8KDM2AKDM4C | |
| SCHEMBL11020183 | 0.94 | METAP2 (0.44) | METAP2KDM5APHF8KDM2AKDM4C | |
| SCHEMBL11020753 | 0.94 | METAP2 (0.44) | METAP2KDM5APHF8KDM2AKDM4C | |
| SCHEMBL11023534 | 0.92 | METAP2 (0.46) | METAP2KDM5APHF8KDM2AKDM4C | |
| SCHEMBL11022081 | 0.92 | METAP2 (0.46) | METAP2KDM5APHF8KDM2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046961-B1 | EPOXY-CYCLOALKYLALKANECARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-02-13 | — | — | EP | disclosed |
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| WO-1982000822-A1 | SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | EISTETTER K | 1982-03-18 | — | — | WO | disclosed |
| EP-0046961-A1 | Epoxy-cycloalkylalkanecarboxylic acids, process for their preparation, their use and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-10 | — | — | EP | disclosed |