Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23982430 | 1.00 | PNP (0.56) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL30555936 | 0.86 | PNP (0.59) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL11021787 | 0.86 | PNP (0.59) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23982196 | 0.82 | — | — | |
| SCHEMBL1795053 | 0.81 | PNP (0.46) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982644 | 0.80 | HIF1A (0.71) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL18862687 | 0.80 | HIF1A (0.71) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL21563936 | 0.80 | HIF1A (0.71) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL21563846 | 0.80 | HIF1A (0.71) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL30818467 | 0.80 | HIF1A (0.71) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038569-B1 | DEAZAPURINE NUCLEOSIDES, FORMULATIONS AND PREPARATION THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-01-30 | — | — | EP | disclosed |
| US-4481197-A | ANTIARTHRITIC, ANTIBODY INHIBITORS | BURROUGHS WELLCOME CO. (US) | 1984-11-06 | — | — | US | disclosed |
| US-4381344-A | Process for producing deoxyribosides using bacterial phosphorylase | BURROUGHS WELLCOME CO. (US) | 1983-04-26 | — | — | US | disclosed |
| EP-0038569-A2 | Deazapurine nucleosides, formulations and preparation thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-10-28 | — | — | EP | disclosed |