SCHEMBL30555936

SCHEMBL30555936

Nc1nccc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PNP P00491 1/20 0.59
▸ LMNA P02545 1/20 0.59
▸ TP53 P04637 1/20 0.59
▸ HTT P42858 1/20 0.59
▸ PDE4D Q08499 1/20 0.59
▸ PDE3A Q14432 1/20 0.59
▸ SMN1; SMN2 Q16637 1/20 0.59
▸ RXFP1 Q9HBX9 1/20 0.59
▸ AHCY P23526 4/20 0.58
▸ PIM1 P11309 1/20 0.56
▸ CSNK2A2 P19784 1/20 0.56
▸ CSNK2B P67870 1/20 0.56
▸ CSNK2A1 P68400 1/20 0.56
▸ CSNK2A3 Q8NEV1 1/20 0.56
▸ ADRB1 P08588 1/20 0.56
▸ DNMT1 P26358 1/20 0.56
▸ HIF1A Q16665 1/20 0.52
▸ EZH2 Q15910 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11021787 1.00 PNP (0.59) PNPLMNATP53HTTPDE4D
SCHEMBL9128072 0.87 AHCY (0.54) PNPLMNATP53HTTPDE4D
SCHEMBL9128081 0.87 AHCY (0.54) PNPLMNATP53HTTPDE4D
SCHEMBL23982430 0.86 PNP (0.56) PNPLMNATP53HTTPDE4D
SCHEMBL11024161 0.86 PNP (0.56) PNPLMNATP53HTTPDE4D
SCHEMBL23620769 0.82 PNP (0.58) PNPLMNATP53HTTPDE4D
SCHEMBL31650732 0.81 DNMT1 (0.50) PNPLMNATP53HTTPDE4D
Deoxyadenosine SCHEMBL19877 0.80 HIF1A (0.71) PNPLMNATP53HTTPDE4D
Deoxyadenosine SCHEMBL193181 0.80 HIF1A (0.71) PNPLMNATP53HTTPDE4D
Deoxyadenosine SCHEMBL23982174 0.80 HIF1A (0.71) PNPLMNATP53HTTPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 — — CN claimed
WO-2025132708-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF HUNTINGTON'S DISEASE PROQR THERAPEUTICS II B.V. (NL) 2025-06-26 — — WO disclosed
EP-4555086-A1 OLIGONUCLEOTIDES FOR ADAR-MEDIATED RNA EDITING AND USE THEREOF ProQR Therapeutics II B.V. (NL) 2025-05-21 — — EP disclosed
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