Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.57 |
| ▸ | EBP | Q15125 | 3/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11023197 | 0.88 | SIGMAR1 (0.59) | SIGMAR1EBPSLC6A4CHRM2KCNH2 | |
| SCHEMBL11024266 | 0.84 | SIGMAR1 (0.60) | SIGMAR1EBPSLC6A4CHRM2KCNH2 | |
| SCHEMBL11207812 | 0.82 | SIGMAR1 (0.56) | SIGMAR1EBPSLC6A4CHRM2KCNH2 | |
| Hydrochloric Acid SCHEMBL11024902 | 0.81 | SIGMAR1 (0.55) | SIGMAR1EBPSLC6A4CHRM2KCNH2 | |
| SCHEMBL11024413 | 0.81 | SIGMAR1 (0.46) | SIGMAR1SLC6A4CHRM2KCNH2SLC6A2 | |
| Hydrochloric Acid SCHEMBL11023899 | 0.81 | SIGMAR1 (0.57) | SIGMAR1EBPSLC6A4CHRM2KCNH2 | |
| Hydrochloric Acid SCHEMBL11020878 | 0.80 | SIGMAR1 (0.56) | SIGMAR1EBPSLC6A4CHRM2KCNH2 | |
| Hydrochloric Acid SCHEMBL11026255 | 0.79 | SIGMAR1 (0.53) | SIGMAR1EBPSLC6A4CHRM2KCNH2 | |
| Hydrochloric Acid SCHEMBL11022697 | 0.79 | SIGMAR1 (0.53) | SIGMAR1EBPSLC6A4CHRM2KCNH2 | |
| Hydrochloric Acid SCHEMBL11025785 | 0.78 | SIGMAR1 (0.52) | SIGMAR1EBPSLC6A4CHRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082266-B1 | SUBSTITUTED 1,5-DIAMINOPENTANES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1985-01-09 | — | — | EP | disclosed |